Professor Tofazzal Islam is an internationally reputed researcher in molecular plant-microbe interactions, agricultural and nanobiotechnology. Currently, he is the Head of Plant Biotechnology Discipline of the Institute of Biotechnology and Genetic Engineering (IBGE) of Bangabandhu Sheikh Mujibur Rahman Agricultural University, Bangladesh. He is the founding Director of the IBGE. His team uses both classical and frontier research methods for dissecting molecular cross-talks between plant and associated microorganisms. He obtained B.Sc.Ag. (Hons.) and M.Sc.(Ag.) degrees from Bangladesh Agricultural University securing first position in the first class in both the cases. He did MS and PhD at Hokkaido University, Japan. Dr Islam conducted postdoctoral research at Hokkaido University, University of Goettingen (Germany), University of Nottingham (UK) and West Virginia University (USA) under the fellowship programs of JSPS, Alexander von Humboldt, Commonwealth and Fulbright, respectively. Prof. Islam discovered a large number (>50) of bioactive secondary metabolites from the host and non-host organisms that are involved in chemotaxis, motility behavior, differentiation, and biorational management of economically important oomycete phytopathogens (e.g., Phytophthora, Aphanomyces, Plasmopara) and fungi. Another important area of his research accomplishment is the discovery of probiotic bacteria and their applications in sustainable agriculture and industry. He has been leading a large group of national and international researchers for the mitigation of worrisome wheat blast disease caused by Magnaporthe oryzae Trticum since its first epidemic outbreak in Bangladesh in 2016 using genomics, genome editing and other advanced molecular approaches. He collaborated Prof. Sophien Kamoun, FRS and Prof. Nick Talbot, FRS, and led many international scientists to rapidly determine the origin of wheat blast in Bangladesh. His team developed a convenient method for the diagnosis of wheat blast fungus in collaboration with researchers in China and USA using CRISPR-Cas12a technology. He advocates and practices open data sharing, open science and international collaborative approaches for tackling the plant health emergencies (such as wheat blast) associated with global food security. He is the Editor-in-Chief of two series books, Bacilli and Agrobiotechnology, and CRISPR-Cas Methods that publish by Springer Nature. He serves as an Academic Editor of PLOS ONE and Associate Editor of Frontiers in Microbiology. An elected Fellow of Bangladesh Academy of Sciences (FBAS), Prof. Islam received by many awards, prizes and medals including a Gold Medal of Bangladesh Academy of Sciences, UGC Research Awards, Commonwealth Innovation Award (UK), Transformer Road Show Innovation Award from Islamic Development Bank and among others for his outstanding academic and research accomplishments. He published more than 250 articles in international journals and books with 4,400+ citations (h-index 35, i10-index 100; and RG Score 44.02). Prof. Islam supervised a good number of Postdoc, Ph D and MS fellows and has been mentoring a large number of young scholars. His current research foci include genomics, genome editing, plant probiotics and nanobiotechnology. Further details of Professor Islam can be known through visiting at https://ibge.bsmrau.edu.bd/tofazzal/.